MUSA TARTIK

Dr. Öğr. Üyesi MUSA TARTIK

Unvan DOKTOR ÖĞRETİM ÜYESİ
Birim FEN-EDEBİYAT FAKÜLTESİ
E-Posta mtartik@bingol.edu.tr
Dahili No 5790

Özgeçmiş

LinkedIn · ORCID

WORK HISTORY

02/2024 - Current

VISITING RESEARCHER, UNC School of Medicine (Chapel Hill, NC, USA)

  • Investigate EdU/5FU DNA damage and repair on different cell lines
  • Presentation of research findings in weekly seminars.
  • Wrote research reports and manuscripts.

09/2020 – Current

RESEARCH ASSOCIATE, BINGOL UNIVERSITY (Bingol, TURKIYE)

  • Teaching activities (30 %)
  • Research activities (70 %)
  • Writing grant proposals and research papers // yeast synthetic biology
  • Supervising and academically mentoring graduate and undergraduate students.

09/2019 - 09/2020

VISITING RESEARCHER, CHALMERS UNIVERSITY OF TECHNOLOGY (Goteborg, SWEDEN)

  • Designed and conduction of two research projects about flavonoid production in budding yeast.
  • Presentation of research findings in weekly seminars.
  • Wrote research reports and manuscripts.
  • Supervised and academically mentored 1 PhD student.

08/2018 – 09/2019

RESEARCH ASSOCIATE,  BINGOL UNIVERSITY (Bingol, TURKIYE)

  • Teaching activities (30 %)
  • Research activities (70 %)
  • Wrote grant proposals and research papers.
  • Supervised and academically mentored graduate and undergraduate students.
  • Funded by CRDF Global to increase the biosafety and biosecurity levels of the department laboratories

08/2011 – 08/2018

RESEARCH ASSISTANT, BINGOL UNIVERSITY (Bingol, TURKIYE)

  • Wrote research papers and presented research findings at conferences.
  • Assisted in the process of conducting education, training and research activities in the department.
  • Responsible for the construction of the laboratory infrastructure.
  • Responsible for ordering and purchasing chemicals, equipment etc.

Öğrenim Bilgisi

EDUCATION

02/2018

Doctor of Philosophy (PhD), BINGOL UNIVERSITY

Thesis: Determination of Saccharomyces cerevisiae resistant to PCM obtained by inverse metabolic strategy and trans-effect of its metabolites on PC3

07/2013

Master of Science (MSc), ISTANBUL TECHNICAL UNIVERSITY

Thesis: Molecular characterization of a boron-resistant yeast mutant obtained by evolutionary engineering

06/2011

Bachelor of Science (BSc), ISTANBUL TECHNICAL UNIVERSITY

Thesis: Analysis of diploidization behaviour in ethanol-resistant yeast

Son Bir Yılda Verilen Dersler

LECTURES

Undergraduate

  • Scientific Principles: Research and Writing 
  • Academic English for Scientific Reading and Writing 
  • From Molecules to Ecosystems 
  • Forensic Genetics 
  • Synthetic Biology
  • Seminar
  • Graduation Project

Uluslararası Hakemli Dergilerde Yayınlanan Makaleler

PUBLICATIONS

KEY Publications with the peer review process

Tartik, M., (2024) The priority of yeast to select among various DNA options to repair genome breaks by homologous recombination: Mol Biol Rep. 51: 99. SPRINGER

Tartik, M., Liu, J., Mohedano, MT., Mao, J., Chen, Y. (2023) Optimizing yeast for high-level production of kaempferol and quercetin: Microbial Cell Factories. 22(1): 74. SPRINGER

Aykutoglu, G., Tartik, M., Darendelioglu, E., Baydas, G. (2020) Melatonin and vitamin E alleviate homocysteine‐induced oxidative injury and apoptosis in endothelial cells: Molecular Biology Reports. 47: 5285–5293 . SPRINGER

Darendelioglu, E., Aykutoglu, G., Tartik, M., Baydas, G. (2016) Turkish propolis protects human endothelial cells in vitro from homocysteine-induced apoptosis. Acta Histochemica. 118(4): 369-376. ELSEVIER

Tartik, M., Aykutoglu, G., Darendelioglu, E., Baydas, G. (2016) Turkish propolis suppresses MCF-7 cell death induced by homocysteine: Biomedicine & Pharmacotherapy. 82: 704-712. ELSEVIER

Ulusal Hakemli Dergilerde Yayınlanan Makaleler

PUBLICATIONS

KEY Publications with the peer review process

Tartik, M. (2023) The preference priority of Bacillus subtilis in uptaking free DNA during the natural transformation. Trakya Univ J Nat Sci, 24(1): 31-39. TUJNS

Tartik, M., Baydas G., Ciftci, M. (2018) Evolutionary-obtained Saccharomyces cerevisiae, resistant to DMEM cultured with prostate cancer cells: Turkish Journal of Nature and Science. 7(1): 11-17. TRDIZIN

Tartik, M., Aykutoglu, G., Darendelioglu, E., Baydas, G. (2015) The various biological activities of Rheum ribes extract on different types of cell: Turkish Journal of Nature and Science. 4 (2): 1-7. TRDIZIN

 

Araştırma Projeleri

RESEARCH 

My research is based on metabolism engineering via synthetic biology applications. We are mostly interested in constructing microbial cell factories for certain purposes. Have a look at the following papers if you are interested in the topic. Synthetic biology includes four steps: Design, Build, Test and Learn. 

System Biology 1/2  and Synthetic Biology 1

The importance of synthetic biology

A sustainable world is possible if all required components can be supplied in an easy, cheap and healthy way. Researchers are working on several approaches to achieve sustainable goals covering all technically, pharmaceutically or medically relevant products. Synthetic production of these compounds in non-native hosts, e.g. bacteria or yeasts, can provide economic and ecological advantages. 

Example of various synthetic biology tools at different alteration... | Download Scientific Diagram

System and synthetic biology are important approaches to developing sustainable next-generation biotechnology at the global level. Our country/region is not free from this situation. The system biology approach is suggesting a deep understanding of the whole system instead of individual sub-parts. Thus, it is easy to handle any trouble related to the system and also manipulate it for a certain purpose. The success of synthetic biology strategies is strongly associated with system biology due to applying regard to data collected by system biology approaches.

PROJECTS

Principal Investigator (PI) - Microplastic Patrol: Yeast Biosensor - TUBITAK 1001 124Z933 - 2025-2028 

Researcher - Chrysotile asbestos bactosensor prototype development  - TUBITAK 1001- 124Z040 - 2024-2027

Researcher - Development of yeasts integrated with the carotenoid zeaxanthin biosynthesis pathway and/or multiple mycotoxin biodegradation pathways (Alfatoxin and Orchratoxin) as feed additives and investigation of their usage possibilities in broilers and laying hens - TUBITAK 1003 - 123R062 - 2023-2026

Principal Investigator (PI) - Yeast engineering for flavonoid production- TUBITAK 3501 222Z269 - 2023-2026

Principal Investigator (PI) - Biosynthetic construction of RAG-mediated recombination in yeast - TUBITAK 1001 122Z281 - 2022-2025

Principal Investigator (PI) - DNA Selection Algorithm of Bacteria with Natural Transformation Feature - BINGOL UNIVERSITY - BAP-FEF.2019.00.0 - 2019-2022

Principal Investigator (PI) - Improvement Biosafety and Biosecurity Level of Local Laboratories - CRDF Global - 2018-2019

Researcher - Determination of Saccharomyces cerevisiae resistant to PCM obtained by inverse metabolic strategy and trans-effect of its metabolites on PC3 - BINGOL UNIVERSITY - FEF.4.16.001 - 2016-2018

Researcher - Investigating the effects of melatonin and alpha-tocopherol on human umbilical cord vein endothelial cells (HUVECs) stressed by hyperhomocysteinemia - BINGOL UNIVERSITY - BAP-261-278-2015 - 2015-2017

Ödüller / Patentler

Aziz Sancar Postdoctoral Fellowship -  - Visiting Scholar - 2023-2025 - UNC School of Medicine - Biochemistry & Biophysics - Sancar Lab - Chapel Hill/NC/USA

TUBITAK 2219 - Post-Doctorate Fellowship - 2019-2020 - Chalmers University of Technology - Life Science - Synthetic Biology - Gothenburg/Sweden

Health Security Partners (HSP) - Health Fellowship - 2017-2018 - Public Health Training - Valencia/Spain