Ph.D.                                           Bingol University, Chemistry, Türkiye                                                     2015 - 2020

                                   Synthesis of Chromophore Labeled Novel Amino Acid Conjugates and Their   Dielectrical Properties

 Advisors: Prof. Ahmet Çetin/Prof. Dr. A. Orhan Görgülü

M.S.                               University of Florida,  Chemistry, USA                                                                   2011 - 2013

A Benzotriazole Based Total Synthesis Cyclic Heptapeptide Rolloamide B

  Advisor: Prof. Alan Roy Katritzky

Language Education                     Columbia University, New York City, USA                                           2010 – 2011

          American Language Program                                                                         

B.S.                                               Fırat University, Chemistry, Türkiye                                                       2004 – 2009

•               Associate Professor                                                                                                                  01/2023 – present
•             Assistant Professor                                                                                                                    01/2023 – 07/2023
•                Research Assistant                                                                                                                   06/2015 – 03/2023
• University of Florida, Department of Chemistry                                                             
•             Research Assistant at Katritzky Research Group                                                                        09/2010-06/2014

Florida Üniversitesi- Kimya Bölümü-Florida Center for Heterocyclic Compounds 2011-2014

1. Beyazay B, Çelik H, Özdemir M, Çalışkan E, Koran K, Biryan F. ‘’Development of Methacrylate Polymers with Tyrosine-Coumarin Side Chains: Advancing Optical and Electrical Applications’’ ACS Omega, 10 (8), 8588-8600, 2025.

2. Kaplan A, Çalışkan E, Çapan İ, Tekin S, Qaoud MT, Biryan F, Koran K, Tekin S, Sandal S, Görgülü AO. ‘’ Phosphazene Tripeptide Conjugates: Design, Synthesis, In Vitro Cytotoxicity and Genotoxicity, Molecular Interactions in Binding Pockets on Human Breast and Colon Cancer Cell Lines’’ ChemMedChem, e202400570, 2025.

3. Yücel Y, Şeker FS, Erden BA, Özdemir M, Tekin Ç, Çalışkan E, Tekin S, Koran K, Biryan F. ‘’The First Chalcone Derivatives of Valine‐Based Spiro‐Cyclotriphosphazenes: In Vitro Cytotoxic Properties, Molecular Docking and DNA Damage Mechanism Studies’’ Journal of Biochemical and Molecular Toxicology 39 (4), e70233, 2025.

4. Yücel Y, Koran K, Çalışkan E, Biryan F. ‘’ Novel Functional Copolymer: Design, Synthesis, Click Chemistry Modification, and Evaluation of Dielectric and Thermal Properties’’ Journal of Molecular Structure, 1323, 140715, 2025.

5. Çalışkan E, Tekin S, Biryan F, Koran K, Sandal S, Çapan İ, Görgülü AO. ‘’ Development of Tripeptide-Cyclotriphosphazene Derivatives: In Vitro Cytotoxicity, Genotoxicity Studies and Molecular Docking Analysis within Ovarian and Prostate Cancer Cell Line Receptors’’ Polyhedron, 264, 117261, 2024.

6. Şahin ME, Biryan F, Çalışkan E, Koran K. ‘’ Coumarin–Phosphazenes: Enhanced Photophysical Properties from Hybrid Materials’’ ACS Inorganic Chemistry, 63(24), 11006-11020, 2024.

7. Çalışkan E, Çapan İ, Tekin S, Qaoud MT, Biryan F, Koran K, Sandal S, Görgülü AO. ‘’ Tripeptide linked dispiro cyclotriphosphazene conjugates: Synthesis, molecular docking analysis of compounds binding within cancer cell line receptors and in vitro cytotoxic and genotoxic activities’’ Bioorganic Chemistry, 150, 107621, 2024.

8. Toprak A, Biryan F, Çalışkan E, Koran K. ‘’ Click chemistry modification of copolymers with cysteine amino acid: tunable thermal, electrical properties and kinetic analysis’’ Journal of Polymer Research, 31(6), 173, 2024.

9. Biryan, F, Çalışkan, E, & Koran, K. ‘Synthesis, Characterization, Thermal and Dielectric Properties of Amino Acid-Centered Coumarin and Chalcone Hybrid Structures via Click Reaction’’ Journal of the Institute of Science and Technology, 14(1), 312-325, 2024.

10. Biryan F, Çelik H, Çalışkan E, Koran K. ‘’ Molecular Design of Ferrocene Based Novel Polymer via Click Chemistry and Investigation of Dielectric and Electrical Properties of Organic Schottky Diode’’ European Polymer Journal, 197, 112321, 2023.

11. Çalışkan E, Kaplan, A, Şekerci, G, Çapan, İ, Tekin, S, Erkan, S., Koran, K., Sandal, S., Görgülü, A. O., Journal of Biochemical and Molecular Toxicology, e23388, 2023.

12. Çalışkan E, Koran K, Biryan F. ‘Synthesis of nanographene doped tetra substituted chalcone cyclophosphazenes and their theoretical and electrical properties’ ChemistrySelect, 8(28), e202300962, 2023.

13. Koran K, Çalışkan E, Öztürk DA, Çapan İ, Tekin S, Sandal S, Görgülü AO. ‘The First Peptide Derivatives of Dioxybiphenyl-Bridged Spiro Cyclotriphosphazenes: In Vitro Cytotoxicity Activities and DNA Damage Studies’ Bioorganic Chemistry, 106338, 2023.

14. Biryan F, Çalışkan E, Koran K. ‘Kinetic analysis and dielectric properties of tyrosine-based tripeptide side groups carrying novel methacrylate polymers’ Journal of Polymer Research, 29, 415, 2022.

15. Çalışkan E. ‘New Amino Acid Chalcone Conjugates: Synthesis, Characterization and Dielectric Properties’ Türk Doğa ve Fen Dergisi, vol. 11, no. 3, pp. 155–159, Sep. 2022.

16. Çalışkan E, Biryan F, Koran K, Akman F, Görgülü AO, Çetin A. ‘Synthesis of Cinnamoyl‐Amino Acid Ester Derivatives and Structure‐Activity Relationship Based on Thermal Stability, Dielectric, and Theoretical Analysis’ ChemistrySelect, 7(20), e202200895, 2022.

17. Çalışkan E, Öztürk DA, Koran K, Tekin S, Sanda S, Erkan S, Görgülü AO, Çetin A. ‘Synthesis of new cinnamoyl-amino acid conjugates and in vitro cytotoxicity and genotoxicity studies’ Chemistry&Biodiversity, 19(8), e202200426, 2022.

18. Çalışkan E. ‘Chemoselective Synthesis of Tyrosine-Based Polymers and Comparison of Their Thermal, Kinetic, and Dielectric Properties’ ChemistrySelect, 7(29): e202202010, 2022.

19. Çalışkan E, Biryan F, Koran K. ‘Investigation of Thermal and Electrical Properties of Dipeptides Containing Fmoc Group’ International Journal of Pure Applied Science, 8(1): 91-101, 2022.

20. Çalışkan E, Biryan F, Koran K, Akman F, Görgülü AO, Çetin A. ‘Synthesis of Cinnamoyl‐Amino Acid Ester Derivatives and Structure‐Activity Relationship Based on Thermal Stability, Dielectric, and Theoretical Analysis’ ChemistrySelect, 7(20): e202200895, 2022.

21. Beytur A, Tekin Ç, Çalışkan E, Tekin S, Koran K, Görgülü AO, Sandal S. ‘Hexa-substituted cyclotriphosphazene derivatives containing hetero-ring chalcones: Synthesis, in vitro cytotoxic activity and their DNA damage determination’ Bioorganic Chemistry, 127: 105997, 2022.

22. Sirka L, Doğan H, Bahar MR, Çalışkan E, Tekin S, Uslu H, Koran K, Sandal S, Görgülü AO. ‘’ (E)-1-(4-Hydroxyphenyl)-3-(substituted-phenyl) prop-2-en-1-ones: Synthesis, In Vitro Cytotoxic Activity and Molecular Docking Studies’’ Acta Chimica Slovenica, 69, 2022.

23. Çalışkan E, Biryan F, Koran K. ‘Preparation of a New Acrylamide Polymer Containing Chalcone Croup, Investigation of Its Kinetic and Dielectric Properties’ Journal of the Institute of Science and Technology, 11(4): 2903-2915, 2021

24. Karuk Elmas SN, Aydin D, Savran T, Çalışkan E, Koran K, Arslan FN, Sadi G, Gorgulu AO, Yilmaz I.‘’A Fluorene based Fluorogenic ''Turn-off'' Chemosensor for the Recognition of Cu2⁺ and Fe3⁺: Computational Modeling and Living-cell Application’’ Current Analytical Chemistry, 18: 204-216, 2022.

25. Çalışkan E, Biryan F, Koran K. ‘’Investigation of Thermal and Dielectric Properties of Dipeptide Coated Magnetic Fe3O4 Nanoparticles’’ Turkish Journal of Nature and Science, (10):1, 259 – 268, 2021.

26. Sevgili Ö, Tasyürek LB, Bayindir S, Orak I, Çalışkan E. ‘’The current transformer mechanism and structural properties of novel Al/BODIPY/pSi and Au/BODIPY/pSi heterojunctions’’ Materials Science in Semiconductor Processing, 2021.

27. Doğan H, Bahar MR, Çalışkan E, Tekin S, Uslu H, Akman F, Koran K, Sandal S, Görgülü AO. ‘’Synthesis and spectroscopic characterizations of hexakis [(1-(4′-oxyphenyl)-3-(substituted-phenyl) prop-2-en-1-one)] cyclotriphosphazenes: their in vitro cytotoxic activity, theoretical analysis and molecular docking studies’’ Journal of Biomolecular Structure and Dynamics, 1-15, 2020.

28. Çalışkan E, Koran K, Görgülü AO, Çetin A. ‘’Electrical properties of amino acid substituted novel cinnamic acid compounds’’ Journal of Molecular Structure, 1222, 128830, 2020.

29. Demirol M, Sirka L, Çalışkan E, Biryan F, Koran K, Görgülü AO, Yakuphanoğlu F. ‘’Synthesis and photodiode properties of chalcone substituted metallo-phthalocyanine’’ Journal of Molecular Structure, 1219, 128571, 2020.

30. Tataroğlu A, Koran K, Dere A, Çek N, Çalışkan E, Görgülü AO, Senany N, Al-Ghamdi A, Farooq W A, Yakuphanoglu F. ‘’Metallo-Phthalocyanines Based Photocapacitors’’ Silicon, 11, 1275-1286, 2019.

31. Koran K, Tekin Ç, Çalışkan E, Tekin S, Sandal S, Görgülü AO. ''Synthesis, Structural and Thermal Characterizations and in vitro Cytotoxic Activities of New Cyclotriphosphazene Derivatives'' Phosphorus, Sulfur, and Silicon and the Related Elements, 192, 11002 -1011, 2017.

32. Panda SS, Elagawany M, Marwani MH, Çalışkan E, El Khatib M, Oliferenko A, Alarmy KA, Katritzky AR. “Chemical ligation from O-acyl isopeptides via 8- and 11-membered cyclic transition states” ARKIVOC  (iv) 91-106, 2014.

33. Khatib M, Elagawany M, Çalışkan E, Davis EF, Katritzky AR. “Total Synthesis of Cyclic Heptapeptide Rollamide B” Chemical Communication, 49, 2631-2633, 2013.

• FLOHET-2012 Annual Florida Heterocyclic and Synthetic IUPAC-Sponsored Conference, Poster presentation; ‘’Total Synthesis of Cyclic Heptapeptide Rollamide B’’ Gainesville, FL (PDF)
• 7^th Eurasian Meeting on Heterocyclic Chemistry-2012, Poster presentation; ‘’Total Synthesis of Cyclic Heptapeptide Rollamide B’’  Istanbul, Turkey (PDF)
• FLOHET-2013 Annual Florida Heterocyclic and Synthetic IUPAC-Sponsored Conference, Poster presentation; “Chemical ligation from O-acyl isopeptides via 8- and 11-membered cyclic transition states.”  Gainesville, FL
• American Chemical Society Florida Section – 2013, Poster presentation; ‘’Total Synthesis of Cyclic Heptapeptide Rollamide B’’  Tampa, Florida
• American Chemical Society Spring 2013 Meeting, Poster presentation; ‘’Total Synthesis of Cyclic Heptapeptide Rollamide B’’  New Orleans 
• FLOHET-2014 Annual Florida Heterocyclic and Synthetic IUPAC-Sponsored Conference, Poster presentation; ‘’Synthesis of novel fluorescent labelled amino acid-vitamin conjugates’’ Gainesville, Florida
• 3rd International BAU Drug Design Congress 2015, Poster presentation; “Antitumor activity of cyclophosphazene derivatives on human prostate cancer cell lines” Istanbul (PDF)
• OEMT2016 2nd International Conference on  Organic Electronic Material Technologies '' The Synthesis of Acid Derived Compounds Bearing 1,3,4-oxadiazole-2-thion Ring as Potential Antimicrobial Agents'',17-19 May 2016 Çanakkale/TURKEY  (PDF)    
• PCFM2018 Internatıonal Conference on Physical Chemistry and Functional Materials ''SYNTHESIS OF CHALCONE SUBSTITUTED AMINOACID/PEPTIDE CONJUGATES AND INVESTIGATION OF ELECTRICAL PROPERTIES'' 19-21 June 2018 Elazığ/Turkey (PDF)
•  6^th International Conference on Materials Science and Nanotechnology For Next Generation (MSNG-2019), ''Electrical Properties of Amino Acid Substituted Novel Cinnamic Acid Compounds'', Niğde (PDF)
• 6^th International Conference on Materials Science and Nanotechnology For Next Generation (MSNG-2019), ''Synthesis and Photodiodes Properties of heterocyclic chalcone substituted metallo-phthalocyanine'', Niğde (PDF)

• Journal of the Turkish Chemical Society Section A: Chemistry

• Journal of the Institute of Science and Technology

1. Marmara University, Scientific Research Project: Project Code: ADT-2024-11142 ‘’Investigation of New Active Pharmaceutical Ingredients for Symptomatic Treatment of Parkinson's Disease‘’ Position: Researcher, 04.2024 - 04.2026.
2. The Scientific and Technological Research Council of Turkey (TÜBİTAK), Project No: 123Z942 ‘’Synthesis, Characterisation, In Vitro Cytotoxicity and Investigation of the Potential of New Dipeptide-Chalcone Hybrid Compounds Containing Aromatic Amino Acids as Glutathione S-Transferase Inhibitors’’ Project manager, 04.2024-04.2025.
3. Research Universities Support Program (ADEP) Fırat University: ''Investigation of Structural, Electrical and Photonic Properties of New Type Photodiodes Carrying Phosphazene-Centered Diazo Side Groups'' Position: Researcher
4. CRDF GLOBAL, United States of America: Project No: 001_TUR_17_BSG ''The improvement of laboratories for physical and biological security, and staff training'' Task: Assistant coordinator. 2020.
5. The Scientific and Technological Research Council of Turkey (TÜBİTAK), Project No: 122Z060 ‘’ Determination of Cytotoxic and Genotoxic Effects of Novel Cyclotrophosphazenes Containing Amino Acid-Calcone Hybrid Compounds on Human Cancer Cell Lines” Researcher, 04.2022 – ongoing
6. İnönü University, Scientific Research Council, Project No: TOA-2021-2478 ‘’ Investigation of anticancer and genotoxic properties of hybrid compounds containing new generation amino acid structures and determination of candidate cancer drug molecules’’ Researcher, March 2021 – March 2022
7. İnönü University, Scientific Research Council, Project No: TSG-2020-2183 ‘’ In vitro determination of cytotoxicity and genotoxicity properties of amino acid conjugates’’ Researcher, May 2020 – May 2022
8. The Scientific and Technological Research Council of Turkey (TÜBİTAK) 3001-Research project, Project No: 118Z286 ‘’ Synthesis and investigation of genotoxicity and cytotoxicity of new peptide-substituted cyclotriphasophazenes’’ Researcher, November 2018 – December 2021
9. Bingöl University, Scientific Research Council, Project No:  FEF.2018.00.003 ‘’Synthesis and dielectric properties of new amino acid conjugates labeled with chromophore groups’’ Researcher January 2018 – August 2020
10. Fırat University, Scientific Research Council, Project No:  FF.16.08 ‘’Investigation of electrical properties of organocyclotriphosphazene compounds containing anthracene substituted chalcone groups. Researcher, May 2018 – April 2019
11. The Scientific and Technological Research Council of Turkey (TÜBİTAK) 3001-Research project, Project No: 116Z758 ‘’Synthesis of new phosphazene compounds containing 3-(cinnamoyl)-7-Hydroxy-2H-Chromen-2-ene groups and investigation of their genotoxicity and cytotoxicity against various human cancer cells’’ Researcher, April 2017 – August 2019
12. Fırat University, Scientific Research Council, Project No: FF.16.08 ‘’Investigation of sensor properties of dihydroxycoumarins against metals’’ Researcher, March 2016 – July 2018

1. TUBITAK 2237 Project Writing Training                                                             İnönü University May 2021
2. TUBITAK 2237 Project Writing Training                                                         Fırat University October 2023
3. TUBITAK 2237 Project Writing Training                                                              Fırat University June 2024
4. TUBITAK 2237 Project Writing Training                                                              Fırat University July 2024

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